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Index > Protein center > FUBP1(Gene name) > Human
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  • FUBP1 (Gene name),
  • Far upstream element-binding protein 1 (Protein name ),  FUBP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FUBP1;
    Protein name:
    Far upstream element-binding protein 1(FBP;FUSE-binding protein 1);
    Alternative:
    DNA helicase V(hDH V);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Found in a complex with PUF60 and far upstream element (FUSE) DNA segment. Interacts with PUF60 and JTV1.
    Function:
    Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    644
    Sequence:
    50:
    MADYSTVPPP | SSGSAGGGGG | GGGGGGVNDA | FKDALQRARQ | IAAKIGGDAG | 
    100:
    TSLNSNDYGY | GGQKRPLEDG | DQPDAKKVAP | QNDSFGTQLP | PMHQQQSRSV | 
    150:
    MTEEYKVPDG | MVGFIIGRGG | EQISRIQQES | GCKIQIAPDS | GGLPERSCML | 
    200:
    TGTPESVQSA | KRLLDQIVEK | GRPAPGFHHG | DGPGNAVQEI | MIPASKAGLV | 
    250:
    IGKGGETIKQ | LQERAGVKMV | MIQDGPQNTG | ADKPLRITGD | PYKVQQAKEM | 
    300:
    VLELIRDQGG | FREVRNEYGS | RIGGNEGIDV | PIPRFAVGIV | IGRNGEMIKK | 
    350:
    IQNDAGVRIQ | FKPDDGTTPE | RIAQITGPPD | RCQHAAEIIT | DLLRSVQAGN | 
    400:
    PGGPGPGGRG | RGRGQGNWNM | GPPGGLQEFN | FIVPTGKTGL | IIGKGGETIK | 
    450:
    SISQQSGARI | ELQRNPPPNA | DPNMKLFTIR | GTPQQIDYAR | QLIEEKIGGP | 
    500:
    VNPLGPPVPH | GPHGVPGPHG | PPGPPGPGTP | MGPYNPAPYN | PGPPGPAPHG | 
    550:
    PPAPYAPQGW | GNAYPHWQQQ | APPDPAKAGT | DPNSAAWAAY | YAHYYQQQAQ | 
    600:
    PPPAAPAGAP | TTTQTNGQGD | QQNPAPAGQV | DYTKAWEEYY | KKMGQAVPAP | 
    644:
    TGAPPGGQPD | YSAAWAEYYR | QQAAYYAQTS | PQGMPQHPPA | PQGQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human FBP
    Cat.:
    E15271h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human FBP
    Cat.:
    E15271r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human FBP
    Cat.:
    E15271m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FBP
    Cat.:
    U15271h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FBP
    Cat.:
    U15271m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FBP
    Cat.:
    U15271r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human FBP
    Cat.:
    P15271Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FBP
    Cat.:
    P15271Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FBP
    Cat.:
    P15271Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human FBP
    Monoclonal Antibody for Human FBP
    Monoclonal Antibody for Human FBP
    Protein for Human FBP
    Protein for Human FBP
    Protein for Human FBP

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif."
      Duncan R. , Bazar L. , Michelotti G. , Tomonaga T. , Krutzsch H. , Avigan M. , Levens D.
      Genes Dev.8:465-480(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 192-194; 204-207; 273-280; 285-291; 301-315; 322-329; 395-398; 410-412; 431-439 AND 441-444;FUNCTION
      tissue: Leukemia.
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    4. 4.
      "Identification of human DNA helicase V with the far upstream element-binding protein."
      Vindigni A. , Ochem A. , Triolo G. , Falaschi A.
      Nucleic Acids Res.29:1061-1067(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 45-64; 134-146; 272-284; 309-322; 380-387; 415-425 AND 431-440
    5. 5.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 107-118; 134-146; 163-170; 249-256; 272-293 AND 332-344;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    6. 6.
      "Large-scale proteomic analysis of the human spliceosome."
      Rappsilber J. , Ryder U. , Lamond A.I. , Mann M.
      Genome Res.12:1231-1245(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;IDENTIFICATION BY MASS SPECTROMETRY
    7. 7.
      "The FBP interacting repressor targets TFIIH to inhibit activated transcription."
      Liu J. , He L. , Collins I. , Ge H. , Libutti D. , Li J. , Egly J.-M. , Levens D.
      Mol. Cell5:331-341(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH PUF60 AND FUSE DNA;INTERACTION WITH PUF60
    8. 8.
      "Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation."
      Kim M.J. , Park B.-J. , Kang Y.-S. , Kim H.J. , Park J.-H. , Kang J.W. , Lee S.W. , Han J.M. , Lee H.-W. , Kim S.
      Nat. Genet.34:330-336(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JTV1;UBIQUITINATION;PROTEASOME-MEDIATED DEGRADATION
    9. 9.
      "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
      Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-153 AND SER-630;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    14. 14.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-630;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    15. 15.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-153 AND SER-630;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140 AND SER-630;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "Structure and dynamics of KH domains from FBP bound to single-stranded DNA."
      Braddock D.T. , Louis J.M. , Baber J.L. , Levens D. , Clore G.M.
      Nature415:1051-1056(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 278-447 IN COMPLEX WITH SINGLE-STRANDED FUSE DNA
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